node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCW62216.1 | SCW95061.1 | SAMN05660859_2052 | SAMN05660859_4229 | Hypothetical chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.799 |
SCW62216.1 | SCW95936.1 | SAMN05660859_2052 | SAMN05660859_0152 | Hypothetical chaperone protein. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.998 |
SCW62216.1 | groL | SAMN05660859_2052 | SAMN05660859_0928 | Hypothetical chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.799 |
SCW62216.1 | groL-2 | SAMN05660859_2052 | SAMN05660859_2803 | Hypothetical chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.799 |
SCW62216.1 | groS | SAMN05660859_2052 | SAMN05660859_0929 | Hypothetical chaperone protein. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.835 |
SCW62216.1 | grpE | SAMN05660859_2052 | SAMN05660859_2526 | Hypothetical chaperone protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.993 |
SCW62216.1 | hslU | SAMN05660859_2052 | SAMN05660859_2539 | Hypothetical chaperone protein. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.599 |
SCW62216.1 | hslV | SAMN05660859_2052 | SAMN05660859_2537 | Hypothetical chaperone protein. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.573 |
SCW95061.1 | SCW62216.1 | SAMN05660859_4229 | SAMN05660859_2052 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Hypothetical chaperone protein. | 0.799 |
SCW95061.1 | SCW95936.1 | SAMN05660859_4229 | SAMN05660859_0152 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.840 |
SCW95061.1 | dnaK | SAMN05660859_4229 | SAMN05660859_2332 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.883 |
SCW95061.1 | groS | SAMN05660859_4229 | SAMN05660859_0929 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.994 |
SCW95061.1 | grpE | SAMN05660859_4229 | SAMN05660859_2526 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.890 |
SCW95061.1 | hslU | SAMN05660859_4229 | SAMN05660859_2539 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.766 |
SCW95061.1 | hslV | SAMN05660859_4229 | SAMN05660859_2537 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.706 |
SCW95936.1 | SCW62216.1 | SAMN05660859_0152 | SAMN05660859_2052 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Hypothetical chaperone protein. | 0.998 |
SCW95936.1 | SCW95061.1 | SAMN05660859_0152 | SAMN05660859_4229 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.840 |
SCW95936.1 | dnaK | SAMN05660859_0152 | SAMN05660859_2332 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
SCW95936.1 | groL | SAMN05660859_0152 | SAMN05660859_0928 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.840 |
SCW95936.1 | groL-2 | SAMN05660859_0152 | SAMN05660859_2803 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.840 |