SCW47602.1 protein (Ancylobacter rudongensis)

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Known Interactions

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Predicted Interactions

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gene co-occurrence

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SCW47602.1

Soluble lytic murein transglycosylase. (750 aa)

Predicted Functional Partners:

SCW94625.1

0.559

SCW92455.1

0.552

fliE

0.552

SCW84498.1

0.529

SCW94619.1

0.522

SCW94642.1

0.521

SCW92148.1

0.513

SCW94697.1

0.492

SCW58300.1

0.485

SCW90827.1

0.452

Your Current Organism:

Ancylobacter rudongensis

NCBI taxonomy Id: 177413
Other names: A. rudongensis, Ancylobacter rudongensis Xin et al. 2004, JCM 11671

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCW47602.1	SCW58300.1	SAMN05660859_1402	SAMN05660859_1778	Soluble lytic murein transglycosylase.	Uncharacterized conserved protein.	0.485
SCW47602.1	SCW84498.1	SAMN05660859_1402	SAMN05660859_3124	Soluble lytic murein transglycosylase.	Extensin-like protein C-terminus.	0.529
SCW47602.1	SCW90827.1	SAMN05660859_1402	SAMN05660859_3664	Soluble lytic murein transglycosylase.	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain.	0.452
SCW47602.1	SCW92148.1	SAMN05660859_1402	SAMN05660859_3793	Soluble lytic murein transglycosylase.	Predicted membrane protein.	0.513
SCW47602.1	SCW92455.1	SAMN05660859_1402	SAMN05660859_3854	Soluble lytic murein transglycosylase.	N-acetylmuramoyl-L-alanine amidase.	0.552
SCW47602.1	SCW94619.1	SAMN05660859_1402	SAMN05660859_4116	Soluble lytic murein transglycosylase.	Flagellar hook protein FlgE.	0.522
SCW47602.1	SCW94625.1	SAMN05660859_1402	SAMN05660859_4117	Soluble lytic murein transglycosylase.	Flagellum-specific ATP synthase.	0.559
SCW47602.1	SCW94642.1	SAMN05660859_1402	SAMN05660859_4121	Soluble lytic murein transglycosylase.	Flagellar motor switch protein FliM.	0.521
SCW47602.1	SCW94697.1	SAMN05660859_1402	SAMN05660859_4138	Soluble lytic murein transglycosylase.	Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.	0.492
SCW47602.1	fliE	SAMN05660859_1402	SAMN05660859_4129	Soluble lytic murein transglycosylase.	Flagellar hook-basal body complex protein FliE.	0.552
SCW58300.1	SCW47602.1	SAMN05660859_1778	SAMN05660859_1402	Uncharacterized conserved protein.	Soluble lytic murein transglycosylase.	0.485
SCW84498.1	SCW47602.1	SAMN05660859_3124	SAMN05660859_1402	Extensin-like protein C-terminus.	Soluble lytic murein transglycosylase.	0.529
SCW84498.1	SCW92148.1	SAMN05660859_3124	SAMN05660859_3793	Extensin-like protein C-terminus.	Predicted membrane protein.	0.534
SCW90827.1	SCW47602.1	SAMN05660859_3664	SAMN05660859_1402	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain.	Soluble lytic murein transglycosylase.	0.452
SCW92148.1	SCW47602.1	SAMN05660859_3793	SAMN05660859_1402	Predicted membrane protein.	Soluble lytic murein transglycosylase.	0.513
SCW92148.1	SCW84498.1	SAMN05660859_3793	SAMN05660859_3124	Predicted membrane protein.	Extensin-like protein C-terminus.	0.534
SCW92455.1	SCW47602.1	SAMN05660859_3854	SAMN05660859_1402	N-acetylmuramoyl-L-alanine amidase.	Soluble lytic murein transglycosylase.	0.552
SCW94619.1	SCW47602.1	SAMN05660859_4116	SAMN05660859_1402	Flagellar hook protein FlgE.	Soluble lytic murein transglycosylase.	0.522
SCW94619.1	SCW94625.1	SAMN05660859_4116	SAMN05660859_4117	Flagellar hook protein FlgE.	Flagellum-specific ATP synthase.	0.987
SCW94619.1	SCW94642.1	SAMN05660859_4116	SAMN05660859_4121	Flagellar hook protein FlgE.	Flagellar motor switch protein FliM.	0.988

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

4.94e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009252

Peptidoglycan biosynthetic process

8 of 38

1.96

4.42

8.65e-12

GO:0071555

Cell wall organization

4 of 26

1.83

2.07

2.98e-05

GO:0008360

Regulation of cell shape

4 of 26

1.83

2.07

2.98e-05

GO:0051301

Cell division

3 of 44

1.47

0.99

0.0063

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008955

Peptidoglycan glycosyltransferase activity

5 of 7

2.49

4.05

1.40e-08

GO:0008658

Penicillin binding

4 of 6

2.46

3.21

7.03e-07

GO:0009002

Serine-type D-Ala-D-Ala carboxypeptidase activity

3 of 5

2.42

2.34

3.71e-05

GO:0016757

Glycosyltransferase activity

6 of 61

1.63

2.33

7.03e-07

GO:0004180

Carboxypeptidase activity

4 of 19

1.96

2.32

1.32e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1359

Mixed, incl. Peptidoglycan biosynthesis, and Cell division

11 of 46

2.02

6.54

2.68e-19

CL:1363

Mixed, incl. Peptidoglycan biosynthesis, and Cell division site

9 of 33

2.07

5.85

1.83e-15

CL:1416

Peptidoglycan glycosyltransferase activity, and Peptidoglycan muralytic activity

4 of 5

2.54

3.48

2.33e-07

CL:1365

Mixed, incl. Cell shape, and Cell division site

5 of 23

1.98

3.01

2.35e-07

CL:1398

Mixed, incl. Cell cycle protein, and Cell morphogenesis

2 of 5

2.24

1.07

0.0102

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 33

1.9

3.33

1.15e-08

map01501

beta-Lactam resistance

4 of 121

1.16

0.79

0.0083

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032153

Cell division site

3 of 9

2.16

1.68

0.00059

GOCC:0005618

Cell wall

3 of 21

1.79

1.26

0.0027

GOCC:0071944

Cell periphery

7 of 713

0.63

0.39

0.0319

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0961

Cell wall biogenesis/degradation

3 of 16

1.91

1.38

0.0018

KW-0133

Cell shape

3 of 16

1.91

1.38

0.0018

KW-0997

Cell inner membrane

3 of 42

1.49

0.94

0.0087

KW-0573

Peptidoglycan synthesis

2 of 15

1.76

0.87

0.0198

KW-0328

Glycosyltransferase

2 of 22

1.6

0.73

0.0348

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00905

Penicillin binding protein transpeptidase domain

4 of 6

2.46

2.98

2.11e-06

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.64

1.11

0.0097

PF01098

Cell cycle protein

2 of 2

2.64

1.11

0.0097

PF00912

Transglycosylase

2 of 4

2.34

1.04

0.0120

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001460

Penicillin-binding protein, transpeptidase

4 of 6

2.46

2.92

2.73e-06

IPR012338

Beta-lactamase/transpeptidase-like

5 of 18

2.08

2.84

1.26e-06

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.64

0.98

0.0167

IPR005311

Penicillin-binding protein, dimerisation domain

2 of 2

2.64

0.98

0.0167

IPR001182

Probable peptidoglycan glycosyltransferase FtsW/RodA

2 of 2

2.64

0.98

0.0167

(more ...)

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