Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FTT_0287cSimilar to Q8XIW2 Hypothetical protein CPE2001 from Clostridium perfringens (229 aa). FASTA: opt: 806 Z-score: 994.2 E(): 1.7e-47 Smith-Waterman score: 806; 51.948 identity in 231 aa overlap ORF ftt0287c. (231 aa)    
Predicted Functional Partners:
pdxY
Similar to Q8D4Q2 Pyridoxal/pyridoxine/pyridoxamine kinase from Vibrio vulnificus (290 aa). FASTA: opt: 611 Z-score: 766.0 E(): 8.9e-35 Smith-Waterman score: 611; 38.545identity in 275 aa overlap.
       0.775
FTT_0289c
Hypothetical lipoprotein; ORF ftt0289c.
       0.775
lpxD2
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
       0.580
moxR
Methanol dehydrogenase regulatory protein; Similar to Q87YN6 MoxR protein, putative, from Pseudomonas syringae (319 aa). FASTA: opt: 1309 Z-score: 1518.5 E(): 9.9e-77 Smith-Waterman score: 1309; 61.489 identity in 309 aa overlap.
       0.526
FTT_0291
Similar to Q87YN5 Conserved hypothetical protein from Pseudomonas syringae (314 aa). FASTA: opt: 561 Z-score: 693.3 bits: 136.4 E(): 1e-30 Smith-Waterman score: 561; 30.479 identity in 292 aa overlap ORF ftt0291.
       0.509
FTT_0292
Similar to Q8D3W9 Conserved hypothetical protein from Vibrio vulnificus (156 aa). FASTA: opt: 228 Z-score: 276.8 E(): 1.5e-07 Smith-Waterman score: 228; 28.481 identity in 158 aa overlap ORF ftt0292.
       0.509
FTT_0293
Hypothetical membrane protein; Similar to Q88LA6 Von Willebrand factor type A domain protein from Pseuodmonas putida (358 aa). FASTA: opt: 905 Z-score: 1015.4 E(): 1.1e-48 Smith-Waterman score: 905; 45.122 identity in 328 aa overlap ORF ftt0293.
       0.509
Your Current Organism:
Francisella tularensis SCHUS4
NCBI taxonomy Id: 177416
Other names: F. tularensis subsp. tularensis SCHU S4, Francisella tularensis Biovar A str. SCHU S4, Francisella tularensis Biovar A str. Schu 4, Francisella tularensis subsp. tularensis SCHU S4, Francisella tularensis subsp. tularensis Schu 4, Francisella tularensis subsp. tularensis str. SCHU S4, Francisella tularensis subsp. tularensis strain SCHU S4
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