STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FTT_0555Similar to Q930P5 Hypothetical protein RA0150 from Rhizobium meliloti (262 aa). FASTA: opt: 924 Z-score: 1048.2 E(): 1.7e-50 Smith-Waterman score: 924; 54.202 identity in 238 aa overlap. Some similarity to glutaredoxin ORF ftt0555. (243 aa)    
Predicted Functional Partners:
nrdA
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.795
FTT_0554
Similar to Q99SH0 Hypothetical protein SAV2087 from Stafylococcus aureus (97 aa). FASTA: opt: 243 Z-score: 331.6 E(): 1.4e-10 Smith-Waterman score: 243; 45.455 identity in 77 aa overlap ORF ftt0554.
       0.757
msrA1
Major facilitator superfamily (MFS) transport protein, pseudogene; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.702
FTT_0552
Conserved hypothetical protein, pseudogene; Similar to Q92LL0 Hypothetical protein R03032 from Rhizobium meliloti (367 aa). FASTA: opt: 921 Z-score: 1129.8 E(): 4.9e-55 Smith-Waterman score: 921; 44.186 identity in 344 aa overlap. Contains a frameshift after aa 102. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift. ORF ftt0551; Belongs to the aldehyde dehydrogenase family.
   
   0.549
FTT_0553
Similar to Q8EJ53 Conserved hypothetical protein from Shewanella oneidensis (267 aa). FASTA: opt: 859 Z-score: 1057.9 E(): 4.9e-51 Smith-Waterman score: 859; 52.809 identity in 267 aa overlap ORF ftt0553.
       0.527
sodC
Superoxide dismuate (Cu-Zn) precusor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 
 0.492
msrA2
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.482
naoX
Similar to Q8XMF5 NADH oxidase from Clostridium perfringens (566 aa). FASTA: opt: 2055 Z-score: 2177.9 E(): 1.8e-113 57.117 identity in 548 aa overlap.
  
  
 0.472
FTT_0401
Hypothetical protein; Partial homology to carboxy terminus of Q9CLV4a Hypothetical protein PM1097 from Pasteurella multocida (417 aa). FASTA: opt: 269 Z-score: 330.3 E(): 1.7e-10 Smith-Waterman score: 269; 26.050identity in 238 aa overlap ORF ftt0401.
  
     0.418
Your Current Organism:
Francisella tularensis SCHUS4
NCBI taxonomy Id: 177416
Other names: F. tularensis subsp. tularensis SCHU S4, Francisella tularensis Biovar A str. SCHU S4, Francisella tularensis Biovar A str. Schu 4, Francisella tularensis subsp. tularensis SCHU S4, Francisella tularensis subsp. tularensis Schu 4, Francisella tularensis subsp. tularensis str. SCHU S4, Francisella tularensis subsp. tularensis strain SCHU S4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.