Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FTT_0900Conserved hypothetical membrane protein; ORF ftt0900. (123 aa)    
Predicted Functional Partners:
rbn
Similar to RBN_ECOLI (P32146) tRNA processing ribonuclease BN from E. coli (290 aa). FASTA: opt: 535 Z-score: 578.5 E(): 2.5e-24 Smith-Waterman score: 535; 33.813 identity in 278 aa overlap.
      
 0.832
argS
Similar to SYR_SALTY (P74871) Arginyl-tRNA synthetase from Salmonella typhimurium (577 aa). FASTA: opt: 1159 Z-score: 1408.5 E(): 1.5e-70 Smith-Waterman score: 1159; 34.841 identity in 597 aa overlap.
      
 0.832
FTT_1302
Purine/pyrimidine phosphoribosyl transferase family protein, pseudogene; Similar to Q8A404 Putative amidophosphoribosyl-transferase from Bacteroides thetaiotaomicron (235 aa). FASTA: opt: 247 Z-score: 317.1 E(): 9e-10 Smith-Waterman score: 247; 26.699identity in 206 aa overlap. Contains a frameshift after aa 121 ORF ftt1301c.
  
     0.728
FTT_0647c
Similar to Q82WE7 Hypothetical protein from Nitrosomonas europaea (164 aa). FASTA: opt: 383 Z-score: 490.4 E(): 2e-19 Smith-Waterman score: 383; 41.606 identity in 137 aa overlap. ORF ftt0647c.
  
     0.710
FTT_1486c
Similar to AAO91321 (Q83AQ3) Hypothetical protein from Coxiella burnetti (388 aa). FASTA: opt: 858 Z-score: 1007.0 E(): 3.1e-48 Smith-Waterman score: 858 38.504 identity in 361 aa overlap ORF ftt1486c.
  
     0.690
lpnA
Paralog to conserved hypothetical lipoprotein lpnB.
       0.554
prlC
Similar to P27298 Oligopeptidase A from Escherichia coli (680 aa). FASTA: opt: 1936 Z-score: 2040.0 E(): 8.9e-106 Smith-Waterman score: 1936; 43.722 identity in 677 aa overlap.
       0.549
nuoG
NADH dehydrogenase I, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
   
 0.475
FTT_0898c
Similar to Q88N88 Conserved hypothetical protein TIGR002 from Pseudomonas putida (124 aa). FASTA: opt: 291 Z-score: 402.6 E(): 1.6e-14 Smith-Waterman score: 291; 38.938 identity in 113 aa overlap. ORF ftt0898c; Belongs to the UPF0102 family.
       0.424
Your Current Organism:
Francisella tularensis SCHUS4
NCBI taxonomy Id: 177416
Other names: F. tularensis subsp. tularensis SCHU S4, Francisella tularensis Biovar A str. SCHU S4, Francisella tularensis Biovar A str. Schu 4, Francisella tularensis subsp. tularensis SCHU S4, Francisella tularensis subsp. tularensis Schu 4, Francisella tularensis subsp. tularensis str. SCHU S4, Francisella tularensis subsp. tularensis strain SCHU S4
Server load: low (12%) [HD]