| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA1 | cbiA2 | HRM2_00190 | HRM2_42370 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.916 |
| cbiA1 | cbiB | HRM2_00190 | HRM2_45650 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.873 |
| cbiA1 | cbiC | HRM2_00190 | HRM2_00180 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC; Cobalamin (vitamin B12) biosynthesis protein CbiC (precorrin-8X methylmutase). | 0.998 |
| cbiA1 | cbiD | HRM2_00190 | HRM2_00200 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.971 |
| cbiA1 | cbiG | HRM2_00190 | HRM2_02270 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiG; Cobalamin biosynthesis protein CbiG. | 0.887 |
| cbiA1 | cbiL | HRM2_00190 | HRM2_02310 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiL; Precorrin-2 C20-methyltransferase CbiL (S-adenosyl-L- methionine--precorrin-2 methyltransferase); Belongs to the precorrin methyltransferase family. | 0.855 |
| cbiA1 | cobJ | HRM2_00190 | HRM2_02260 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobJ; precorrin-3B C17-methyltransferase CobJ (Precorrin-3 methyltransferase) (Precorrin-3 methylase). | 0.855 |
| cbiA1 | cobL | HRM2_00190 | HRM2_02290 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobL; Decarboxylating precorrin-6Y C5,15-methyltransferase CobL (Precorrin-6 methyltransferase) (Precorrin-6Y methylase). | 0.909 |
| cbiA1 | cobM | HRM2_00190 | HRM2_02280 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobM; Precorrin-4 C11-methyltransferase CobM. | 0.870 |
| cbiA1 | cobQ | HRM2_00190 | HRM2_02240 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.968 |
| cbiA2 | cbiA1 | HRM2_42370 | HRM2_00190 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.916 |
| cbiA2 | cbiB | HRM2_42370 | HRM2_45650 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.866 |
| cbiA2 | cbiC | HRM2_42370 | HRM2_00180 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC; Cobalamin (vitamin B12) biosynthesis protein CbiC (precorrin-8X methylmutase). | 0.991 |
| cbiA2 | cbiD | HRM2_42370 | HRM2_00200 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.866 |
| cbiA2 | cbiG | HRM2_42370 | HRM2_02270 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiG; Cobalamin biosynthesis protein CbiG. | 0.879 |
| cbiA2 | cbiL | HRM2_42370 | HRM2_02310 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiL; Precorrin-2 C20-methyltransferase CbiL (S-adenosyl-L- methionine--precorrin-2 methyltransferase); Belongs to the precorrin methyltransferase family. | 0.850 |
| cbiA2 | cobJ | HRM2_42370 | HRM2_02260 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobJ; precorrin-3B C17-methyltransferase CobJ (Precorrin-3 methyltransferase) (Precorrin-3 methylase). | 0.854 |
| cbiA2 | cobL | HRM2_42370 | HRM2_02290 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobL; Decarboxylating precorrin-6Y C5,15-methyltransferase CobL (Precorrin-6 methyltransferase) (Precorrin-6Y methylase). | 0.905 |
| cbiA2 | cobM | HRM2_42370 | HRM2_02280 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobM; Precorrin-4 C11-methyltransferase CobM. | 0.867 |
| cbiA2 | cobQ | HRM2_42370 | HRM2_02240 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.953 |