STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltA1GltA1; Citrate (si)-synthase GltA1; Belongs to the citrate synthase family. (431 aa)    
Predicted Functional Partners:
acnA
AcnA; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.989
pdhC
PdhC; Dihydrolipoamide acetyltransferase PdhC (pyruvate dehydrogenase complex, E2 component).
  
 0.969
fumA
FumA; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.962
acsM2
AcsM2; middle-chain-fatty-acid-acyl-CoA synthetase AcsM2 (AMP-binding protein).
  
 0.954
acsA1
AcsA1; acetyl-CoA synthetase/acetate-CoA ligase AcsA1 (AMP-binding protein).
  
 0.954
acsM4
AcsM4; middle-chain-fatty-acid-acyl-CoA synthetase AcsM4 (AMP-binding protein).
  
 0.954
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
  
 
 0.944
pcb
Pcb; Pyruvate carboxylase Pcb (Pyruvic carboxylase) (PCB).
  
 
 0.937
sucC1
SucC1; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.935
atoB1
AtoB1; acetyl-CoA acetyltransferase AtoB1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.929
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.