close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppsA1PpsA1; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase PpsA1 (PEP synthase). (1001 aa)    
Predicted Functional Partners:
gdhA1
GdhA1; NADP-specific glutamate dehydrogenase GdhA (NADP-GDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
   
 0.839
aspC1
AspC1; Aspartate aminotransferase AspC (Transaminase A) (ASPAT).
  
   
 0.623
ACN13714.1
Putative permease (DMT super family).
 
     0.567
eno
Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.556
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
     
 0.504
pyk
Pyk; Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
  
   
 0.497
ACN13447.1
Putative DNA-binding response regulator.
 
    0.484
ACN15064.1
Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.482
gpmA2
GpmA2; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.416
gltB2
GltB2; Glutamate synthase [NADPH], large chain (NADPH-GOGAT).
  
  
 0.415
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
Server load: low (22%) [HD]