STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdDNrdD; Anaerobic ribonucleoside-triphosphate reductase NrdD. (696 aa)    
Predicted Functional Partners:
pflA
PflA; Pyruvate-formate lyase-activating enzyme PflA.
  
 0.996
ndk
Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.916
pyrG
PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.913
relA
RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.904
cyaA2
CyaA2; Adenylate cyclase CyaA (ATP pyrophosphate-lyase) (Adenylyl cyclase).
    
  0.903
ACN15540.1
Two-component hybrid protein, sensory box hisitidine kinase/adenylate cyclase.
    
  0.902
ACN13571.1
Hypothetical protein; Belongs to the dGTPase family. Type 2 subfamily.
    
  0.900
ACN14302.1
Adenylate cyclase family protein.
     
  0.900
ACN15495.1
dGTP-triphosphohydrolase Dgt (deoxyguanosinetriphosphate triphosphohydrolase protein, dGTPase); Belongs to the dGTPase family. Type 2 subfamily.
    
  0.900
ACN15541.1
Hypothetical protein.
     
  0.900
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
Server load: medium (46%) [HD]