| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACN13633.1 | apt1 | HRM2_05190 | HRM2_05200 | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.990 |
| ACN13633.1 | guaA1 | HRM2_05190 | HRM2_18870 | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.651 |
| ACN13633.1 | hpt | HRM2_05190 | HRM2_32180 | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.427 |
| adeC | apt1 | HRM2_24620 | HRM2_05200 | AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.944 |
| adeC | guaA1 | HRM2_24620 | HRM2_18870 | AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.535 |
| adeC | hpt | HRM2_24620 | HRM2_32180 | AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.932 |
| adk | apt1 | HRM2_17050 | HRM2_05200 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.932 |
| adk | gmk | HRM2_17050 | HRM2_18460 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.873 |
| adk | guaA1 | HRM2_17050 | HRM2_18870 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.586 |
| adk | hpt | HRM2_17050 | HRM2_32180 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.946 |
| adk | purB | HRM2_17050 | HRM2_27090 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.956 |
| adk | ushA | HRM2_17050 | HRM2_09650 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | UshA; UDP-sugar hydrolase / 5'-nucleotidase UshA [precursor]; Belongs to the 5'-nucleotidase family. | 0.906 |
| apt1 | ACN13633.1 | HRM2_05200 | HRM2_05190 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | 0.990 |
| apt1 | adeC | HRM2_05200 | HRM2_24620 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.944 |
| apt1 | adk | HRM2_05200 | HRM2_17050 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.932 |
| apt1 | gmk | HRM2_05200 | HRM2_18460 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
| apt1 | guaA1 | HRM2_05200 | HRM2_18870 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.990 |
| apt1 | hpt | HRM2_05200 | HRM2_32180 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.925 |
| apt1 | purB | HRM2_05200 | HRM2_27090 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.949 |
| apt1 | purH1 | HRM2_05200 | HRM2_33050 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ]. | 0.944 |