STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysE1CysE1; Serine O-acetyltransferase CysE1 (bacterial transferase hexapeptide repeat family). (325 aa)    
Predicted Functional Partners:
cysA1
CysA1; Cysteine synthase CysA1 (O-acetylserine sulfhydrylase A).
 
 0.998
cysS3
CysS3; cysteinyl-tRNA synthetase CysS3 (cysteine--tRNA ligase) (CysRS).
 
 0.986
cysE2
CysE2; Serine O-acetyltransferase CysE2 (bacterial transferase hexapeptide repeat family).
  
  
 
0.923
serB
SerB; Phosphoserine phosphatase SerB (PSP).
    
 0.876
hom
Homoserine dehydrogenase Hom.
  
  
 0.844
glyA
GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.831
ACN14464.1
Phosphoserine phosphatase.
    
 0.829
ACN17636.1
Probable aspartokinase (Aspartate kinase); Belongs to the aspartokinase family.
    
 0.824
ACN17597.1
Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.821
trpA
TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.816
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.