STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fba1Fba1; Fructose-bisphosphate aldolase Fba. (348 aa)    
Predicted Functional Partners:
tpi
Tpi; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.961
gap1
Gap1; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.951
gap2
Gap2; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.951
gap4
Gap4; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.951
pgi
Pgi; Glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); Belongs to the GPI family.
   
 0.943
tkt1
Tkt1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.937
talC
TalC; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.936
eno
Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.929
pfkA
ABC-type branched-chain amino acid transporter, periplasmic substrate-binding protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
  
 0.928
pfp
Pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfb.
  
 0.928
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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