STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fba2Fba2; Fructose-bisphosphate aldolase Fba. (326 aa)    
Predicted Functional Partners:
pfkB1
PfkB1; Carbohydrate kinase family protein PfkB1; Belongs to the carbohydrate kinase PfkB family.
 
 0.988
gap1
Gap1; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.981
tpi
Tpi; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.979
eno
Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.966
gap2
Gap2; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.961
gap4
Gap4; Glyceraldehyde-3-phosphate dehydrogenase Gap (GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.961
tkt1
Tkt1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.954
fbp1
Fbp1; Fructose-1,6-bisphosphatase Fbp.
    
 0.953
pgi
Pgi; Glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); Belongs to the GPI family.
  
 
 0.953
talC
TalC; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.950
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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