STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioFBioF; 7-keto-8-aminopelargonate synthetase BioF. (406 aa)    
Predicted Functional Partners:
glyA
GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.943
gcvP2
GcvP2; Glycine cleavage system, dehydrogenase subunit GcvP2.
 
 
 0.934
gcvP1
GcvP1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
 
 
 0.933
ltaE
LtaE; Low specificity L-threonine aldolase LtaE.
  
 
 0.922
ACN13932.1
Aminotransferase, class V (putative purine catabolism protein PucG).
    
 0.920
soxB1
SoxB1; Sarcosine oxidase, subunit beta.
  
 
 0.917
caiC3
CaiC3; acyl-CoA synthetase (AMP-forming)/AMP-acid ligase CaiC.
 
 
 0.898
ACN16274.1
Predicted polyketide synthase.
  
 
 0.801
ACN16945.1
NAD-dependent nucleotide-diphosphate-sugar epimerase family protein.
 
  
 0.773
ACN14016.1
Hypothetical protein.
       0.732
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.