| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACN15756.1 | ushA | HRM2_26620 | HRM2_09650 | Putative hydrolase of the alpha/beta superfamily; Belongs to the CinA family. | UshA; UDP-sugar hydrolase / 5'-nucleotidase UshA [precursor]; Belongs to the 5'-nucleotidase family. | 0.919 |
| apt1 | apt2 | HRM2_05200 | HRM2_38820 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Apt2; Adenine phosphoribosyltransferase Apt. | 0.900 |
| apt1 | guaA1 | HRM2_05200 | HRM2_18870 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.990 |
| apt1 | hpt | HRM2_05200 | HRM2_32180 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.925 |
| apt1 | purA | HRM2_05200 | HRM2_17430 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.450 |
| apt1 | purB | HRM2_05200 | HRM2_27090 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.949 |
| apt1 | ushA | HRM2_05200 | HRM2_09650 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | UshA; UDP-sugar hydrolase / 5'-nucleotidase UshA [precursor]; Belongs to the 5'-nucleotidase family. | 0.912 |
| apt1 | xpt | HRM2_05200 | HRM2_02560 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.900 |
| apt2 | apt1 | HRM2_38820 | HRM2_05200 | Apt2; Adenine phosphoribosyltransferase Apt. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
| apt2 | guaA1 | HRM2_38820 | HRM2_18870 | Apt2; Adenine phosphoribosyltransferase Apt. | GuaA1; Catalyzes the synthesis of GMP from XMP. | 0.990 |
| apt2 | hpt | HRM2_38820 | HRM2_32180 | Apt2; Adenine phosphoribosyltransferase Apt. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.923 |
| apt2 | purA | HRM2_38820 | HRM2_17430 | Apt2; Adenine phosphoribosyltransferase Apt. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.435 |
| apt2 | purB | HRM2_38820 | HRM2_27090 | Apt2; Adenine phosphoribosyltransferase Apt. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.948 |
| apt2 | ushA | HRM2_38820 | HRM2_09650 | Apt2; Adenine phosphoribosyltransferase Apt. | UshA; UDP-sugar hydrolase / 5'-nucleotidase UshA [precursor]; Belongs to the 5'-nucleotidase family. | 0.912 |
| apt2 | xpt | HRM2_38820 | HRM2_02560 | Apt2; Adenine phosphoribosyltransferase Apt. | Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.900 |
| guaA1 | apt1 | HRM2_18870 | HRM2_05200 | GuaA1; Catalyzes the synthesis of GMP from XMP. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.990 |
| guaA1 | apt2 | HRM2_18870 | HRM2_38820 | GuaA1; Catalyzes the synthesis of GMP from XMP. | Apt2; Adenine phosphoribosyltransferase Apt. | 0.990 |
| guaA1 | guaB | HRM2_18870 | HRM2_24800 | GuaA1; Catalyzes the synthesis of GMP from XMP. | GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA1 | hpt | HRM2_18870 | HRM2_32180 | GuaA1; Catalyzes the synthesis of GMP from XMP. | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
| guaA1 | purA | HRM2_18870 | HRM2_17430 | GuaA1; Catalyzes the synthesis of GMP from XMP. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.930 |
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