Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mcmLMcmL; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1091 aa)    
Predicted Functional Partners:
sbm
Sbm; Homodimeric methylmalonyl-CoA mutase Sbm (MCM-alpha).
 
 
0.998
argK
ArgK; LAO/AO transport system kinase.
 
 
0.986
ACN14114.1
Transcriptional regulator (TetR-family protein).
 
 
 
 0.834
ACN15261.1
acetyl-CoA hydrolase/transferase family protein.
  
  
 0.833
fadB
FadB; 3-hydroxyacyl-CoA dehydrogenase FadB.
 
  
 0.817
pcb
Pcb; Pyruvate carboxylase Pcb (Pyruvic carboxylase) (PCB).
     
 0.763
ACN13616.1
Putative 4-hydroxybutyrate CoA-transferase.
  
  
 0.737
atoB2
AtoB2; acetyl-CoA acetyltransferase AtoB2; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.715
fumA
FumA; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.713
cat3
Cat3; 4-hydroxybutyrate coenzyme A transferase.
  
  
 0.692
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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