STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnAAcnA; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (882 aa)    
Predicted Functional Partners:
icd
Icd; NADP-dependent isocitrate dehydrogenase Icd.
 
 0.997
gltA4
GltA4; Citrate (si)-synthase GltA3; Belongs to the citrate synthase family.
 
 0.994
gltA1
GltA1; Citrate (si)-synthase GltA1; Belongs to the citrate synthase family.
 
 0.989
citC
CitC; NADP-dependent isocitrate dehydrogenase CitC (Oxalosuccinate decarboxylase) (IDH).
 
 0.989
gltA3
GltA3; Citrate (si)-synthase GltA2; Belongs to the citrate synthase family.
 
 0.989
ispH
IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.888
sdhB
SdhB; Succinate dehydrogenase/fumarate reductase, iron-sulfur containing subunit SdhB.
  
 
 0.868
rplS
RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.860
rpmB
RpmB; 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.858
rnc
Two domain fusion protein Includes: metal-dependent phosphoesterase / ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
 
 0.856
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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