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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrcAMrcA; Penicillin-binding protein 1A [Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase ]. (798 aa)    
Predicted Functional Partners:
ACN14830.1
Penicillin binding family protein.
 
 
0.946
mrcB
MrcB; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.942
ACN15221.1
Peptidase M23/M37 family protein.
 
   
 0.725
ftsW
FtsW; Cell division protein FtsW; Belongs to the SEDS family.
  
   
 0.703
ACN15758.1
Putative metalloendopeptidase; cell wall-binding protein associated metalloendopeptidase.
 
   
 0.693
mltG
Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
   
 0.684
murC
MurC; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.682
ACN14260.1
Putative metallopeptidase.
  
     0.649
pbpA
PbpA; Penicillin-binding protein A [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)].
 
 
 
 0.638
murF
MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
   
 0.632
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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