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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hysAHysA; Periplasmic [NiFeSe] hydrogenase, large subunit precursor HysA; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (504 aa)    
Predicted Functional Partners:
hysB
HysB; Periplasmic [NiFeSe] hydrogenase, small subunit precursor HysB.
 0.999
hynB
HynB; Periplasmic [NiFe] hydrogenase, small subunit HynB.
 
 
 0.986
hyaD1
HyaD1; Hydrogenase expression/formation protein HyaD1.
 
 
 0.946
qmoB
QmoB; Quinone-interacting membrane-bound oxidoreductase complex, subunit QmoB.
  
 
 0.926
hypA
HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.919
ACN17399.1
4Fe-4S iron-sulfur binding protein (ferredoxin).
  
 
 0.918
mvhG
MvhG; F420-non-reducing hydrogenase, iron-sulfur subunit mvhG.
 
 
 0.911
dsrB2
DsrB2; Dissimilatory sulfite reductase complex, beta subunit DsrB2 (Hydrogensulfite reductase beta subunit).
     
 0.902
dsrA2
DsrA2; Dissimilatory sulfite reductase complex, alpha subunit DsrA2 (Hydrogensulfite reductase alpha subunit).
     
 0.902
cdhA
CdhA; Bifunctional acetyl-CoA synthetase/carbon monoxide dehydrogenase, alpha subunit CdhA (corrinoid/iron-sulfur protein).
     
  0.900
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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