Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mvhAMvhA; F420-non-reducing hydrogenase, iron-sulfur subunit mvhA. (449 aa)    
Predicted Functional Partners:
mvhG
MvhG; F420-non-reducing hydrogenase, iron-sulfur subunit mvhG.
 
 
 0.998
hyaD2
HyaD2; Hydrogenase expression/formation protein HyaD2.
 
  
 0.932
mvhD2
MvhD2; F420-non-reducing hydrogenase, iron-sulfur subunit MvhD2 (selenocysteine protein; 4Fe-4S).
 
  
 0.903
nuoF
NuoF; NADH-quinone oxidoreductase, NADH-binding subunit NuoF.
  
 
 0.877
hdrA1
HdrA1; Heterodisulfide reductase HdrA1 (selenocystein protein).
 
  
 0.837
ACN16160.1
Putative fusion protein, heterodisulfide reductase (HdrA) / F420-non-reducing hydrogenase (MvhD).
 
  
 0.755
hypD
HypD; Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
   
 0.731
hypF
HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.728
qmoB
QmoB; Quinone-interacting membrane-bound oxidoreductase complex, subunit QmoB.
  
  
 0.690
hypE
HypE; Hydrogenase expression/formation protein HypE.
 
   
 0.683
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
Server load: low (24%) [HD]