STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
relARelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (716 aa)    
Predicted Functional Partners:
ACN15541.1
Hypothetical protein.
    
 0.936
gmk
Gmk; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.933
rpsF
RpsF; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.930
ndk
Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.923
pyk
Pyk; Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
   
 
 0.912
cyaA2
CyaA2; Adenylate cyclase CyaA (ATP pyrophosphate-lyase) (Adenylyl cyclase).
    
 0.909
ACN15540.1
Two-component hybrid protein, sensory box hisitidine kinase/adenylate cyclase.
  
 
 0.908
nrdA
NrdA; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.906
nrdD
NrdD; Anaerobic ribonucleoside-triphosphate reductase NrdD.
     
 0.904
ACN14302.1
Adenylate cyclase family protein.
     
 0.902
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.