ltaE protein (Desulfobacterium autotrophicum)

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Score

ltaE

LtaE; Low specificity L-threonine aldolase LtaE. (334 aa)

Predicted Functional Partners:

glyA

0.941

ACN13932.1

0.938

thrC

0.930

gcvP2

0.928

gcvP1

0.926

bioF

0.922

soxB1

0.909

ACN14356.1

0.745

putA1

0.743

ACN14354.1

0.738

Your Current Organism:

Desulfobacterium autotrophicum

NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN13932.1	bioF	HRM2_08190	HRM2_09040	Aminotransferase, class V (putative purine catabolism protein PucG).	BioF; 7-keto-8-aminopelargonate synthetase BioF.	0.920
ACN13932.1	gcvP1	HRM2_08190	HRM2_24980	Aminotransferase, class V (putative purine catabolism protein PucG).	GcvP1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.907
ACN13932.1	gcvP2	HRM2_08190	HRM2_24970	Aminotransferase, class V (putative purine catabolism protein PucG).	GcvP2; Glycine cleavage system, dehydrogenase subunit GcvP2.	0.922
ACN13932.1	glyA	HRM2_08190	HRM2_31300	Aminotransferase, class V (putative purine catabolism protein PucG).	GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.944
ACN13932.1	ltaE	HRM2_08190	HRM2_12450	Aminotransferase, class V (putative purine catabolism protein PucG).	LtaE; Low specificity L-threonine aldolase LtaE.	0.938
ACN13932.1	soxB1	HRM2_08190	HRM2_04890	Aminotransferase, class V (putative purine catabolism protein PucG).	SoxB1; Sarcosine oxidase, subunit beta.	0.942
ACN14354.1	ACN14356.1	HRM2_12420	HRM2_12440	Putative acyl CoA dehydrogenase.	Conserved hypothetical protein.	0.773
ACN14354.1	ltaE	HRM2_12420	HRM2_12450	Putative acyl CoA dehydrogenase.	LtaE; Low specificity L-threonine aldolase LtaE.	0.738
ACN14354.1	putA1	HRM2_12420	HRM2_12460	Putative acyl CoA dehydrogenase.	PutA1; Bifunctional protein PutA [Includes: Proline dehydrogenase; P5C dehydrogenase].	0.697
ACN14356.1	ACN14354.1	HRM2_12440	HRM2_12420	Conserved hypothetical protein.	Putative acyl CoA dehydrogenase.	0.773
ACN14356.1	ltaE	HRM2_12440	HRM2_12450	Conserved hypothetical protein.	LtaE; Low specificity L-threonine aldolase LtaE.	0.745
ACN14356.1	putA1	HRM2_12440	HRM2_12460	Conserved hypothetical protein.	PutA1; Bifunctional protein PutA [Includes: Proline dehydrogenase; P5C dehydrogenase].	0.680
bioF	ACN13932.1	HRM2_09040	HRM2_08190	BioF; 7-keto-8-aminopelargonate synthetase BioF.	Aminotransferase, class V (putative purine catabolism protein PucG).	0.920
bioF	gcvP1	HRM2_09040	HRM2_24980	BioF; 7-keto-8-aminopelargonate synthetase BioF.	GcvP1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.933
bioF	gcvP2	HRM2_09040	HRM2_24970	BioF; 7-keto-8-aminopelargonate synthetase BioF.	GcvP2; Glycine cleavage system, dehydrogenase subunit GcvP2.	0.934
bioF	glyA	HRM2_09040	HRM2_31300	BioF; 7-keto-8-aminopelargonate synthetase BioF.	GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.943
bioF	ltaE	HRM2_09040	HRM2_12450	BioF; 7-keto-8-aminopelargonate synthetase BioF.	LtaE; Low specificity L-threonine aldolase LtaE.	0.922
bioF	soxB1	HRM2_09040	HRM2_04890	BioF; 7-keto-8-aminopelargonate synthetase BioF.	SoxB1; Sarcosine oxidase, subunit beta.	0.917
gcvP1	ACN13932.1	HRM2_24980	HRM2_08190	GcvP1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Aminotransferase, class V (putative purine catabolism protein PucG).	0.907
gcvP1	bioF	HRM2_24980	HRM2_09040	GcvP1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	BioF; 7-keto-8-aminopelargonate synthetase BioF.	0.933

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