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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maeMae; NAD/NADP-dependent malate dehydrogenase (malic enzyme) (NAD-ME). (576 aa)    
Predicted Functional Partners:
fumC
FumC; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.965
fumA
FumA; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.962
pyk
Pyk; Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
  
 0.960
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
  
 
 0.953
pcb
Pcb; Pyruvate carboxylase Pcb (Pyruvic carboxylase) (PCB).
    
 0.947
porA2
PorA2; Pyruvate:ferredoxin oxidoreductase, subunit PorA2.
  
 
 0.936
porA3
PorA3; Pyruvate:ferredoxin oxidoreductase, subunit PorA3.
  
 
 0.936
ACN14353.1
Putative pyruvate phosphate dikinase.
 
 
 0.926
aldA
AldA; Aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family.
  
 
 0.923
oadB1
OadB1; Oxaloacetate decarboxylase, beta chain OadB.
    
 0.913
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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