Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
trkA2TrkA2; Potassium uptake system, NAD-binding component. (223 aa)    
Predicted Functional Partners:
trkB
TrkB; Potassium uptake system, membrane component TrkB (Trk family protein).
 
 0.980
lysM2
LysM2; Peptidoglycan-binding protein LysM.
  
    0.754
rsmB
RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.583
trkH
TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
  
 
 0.540
motA1
MotA1; Sodium-driven polar flagellar protein MotA (PomA homolog).
     
 0.504
ACN14745.1
Metal dependent response regulator.
       0.488
hemD
HemD; Porphyrin biosynthesis protein HemD [includes: uroporphyrin-III C-methyltransferase; uroporphyrinogen-III synthase].
  
    0.486
moaE
MoaE; Molybdopterin converting factor, large subunit MoaE.
   
    0.481
selA
SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
   
    0.440
motB1
MotB1; Flagellar motor protein MotB (PomB homolog).
     
 0.437
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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