Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prsA2PrsA2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa)    
Predicted Functional Partners:
tkt1
Tkt1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.948
rplY
RplY; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
  
 0.938
purF
PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.925
rpiB
RpiB; Ribose-5-phosphate isomerase RpiB (phosphoriboisomerase B).
  
 
 0.922
algC
AlgC; Phosphomannomutase/phosphoglucomutase AlgC.
  
 0.922
ACN14882.1
Putative nucleotide diphosphate hydrolase (MutT family hydrolase).
    
 0.908
prsA1
PrsA1; Ribose-phosphate pyrophosphokinase PrsA.
  
  
 
0.907
pgm
Pgm; Phosphoglucomutase (Glucose phosphomutase) (PGM).
   
 
 0.904
ACN16581.1
Predicted nucleoside-diphosphate-sugar pyrophosphorylase.
  
 0.894
pdhC
PdhC; Dihydrolipoamide acetyltransferase PdhC (pyruvate dehydrogenase complex, E2 component).
   
 0.885
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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