thiN protein (Desulfobacterium autotrophicum)

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thiN

ThiN; Thiamine pyrophosphokinase ThiN. (211 aa)

Predicted Functional Partners:

engC

0.935

adk

0.910

phoA

0.900

ACN16754.1

0.647

ACN14909.1

0.588

prmA2

0.507

recX

0.501

thiE

0.457

ACN13547.1

0.453

porA4

0.452

Your Current Organism:

Desulfobacterium autotrophicum

NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN13547.1	thiE	HRM2_04290	HRM2_15370	Putative bifunctional enzyme ThiED (Thiamine-phosphate pyrophosphorylase / Phosphomethylpyrimidine kinase).	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.999
ACN13547.1	thiN	HRM2_04290	HRM2_18060	Putative bifunctional enzyme ThiED (Thiamine-phosphate pyrophosphorylase / Phosphomethylpyrimidine kinase).	ThiN; Thiamine pyrophosphokinase ThiN.	0.453
ACN14909.1	thiN	HRM2_18070	HRM2_18060	Hypothetical protein.	ThiN; Thiamine pyrophosphokinase ThiN.	0.588
ACN16754.1	thiN	HRM2_36960	HRM2_18060	Putative flagellar hook-associated protein.	ThiN; Thiamine pyrophosphokinase ThiN.	0.647
adk	engC	HRM2_17050	HRM2_10180	Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.900
adk	thiN	HRM2_17050	HRM2_18060	Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	ThiN; Thiamine pyrophosphokinase ThiN.	0.910
engC	adk	HRM2_10180	HRM2_17050	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.900
engC	phoA	HRM2_10180	HRM2_01880	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	PhoA; Alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family.	0.900
engC	thiE	HRM2_10180	HRM2_15370	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.912
engC	thiN	HRM2_10180	HRM2_18060	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	ThiN; Thiamine pyrophosphokinase ThiN.	0.935
phoA	engC	HRM2_01880	HRM2_10180	PhoA; Alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family.	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.900
phoA	thiE	HRM2_01880	HRM2_15370	PhoA; Alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family.	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.902
phoA	thiN	HRM2_01880	HRM2_18060	PhoA; Alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family.	ThiN; Thiamine pyrophosphokinase ThiN.	0.900
porA4	thiE	HRM2_49430	HRM2_15370	PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.421
porA4	thiN	HRM2_49430	HRM2_18060	PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.	ThiN; Thiamine pyrophosphokinase ThiN.	0.452
prmA2	thiN	HRM2_11510	HRM2_18060	PrmA2; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	ThiN; Thiamine pyrophosphokinase ThiN.	0.507
recX	thiN	HRM2_18750	HRM2_18060	RecX; Modulates RecA activity; Belongs to the RecX family.	ThiN; Thiamine pyrophosphokinase ThiN.	0.501
thiE	ACN13547.1	HRM2_15370	HRM2_04290	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	Putative bifunctional enzyme ThiED (Thiamine-phosphate pyrophosphorylase / Phosphomethylpyrimidine kinase).	0.999
thiE	engC	HRM2_15370	HRM2_10180	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.912
thiE	phoA	HRM2_15370	HRM2_01880	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	PhoA; Alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family.	0.902

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