STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadD4FadD4; long-chain-fatty-acid--CoA ligase FadD4 (Acetyl-CoA-synthetase) (Acyl-activating enzyme). (549 aa)    
Predicted Functional Partners:
ACN16274.1
Predicted polyketide synthase.
  
 0.887
fadB
FadB; 3-hydroxyacyl-CoA dehydrogenase FadB.
 
 
 0.684
aroA
AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
      0.678
rplF
RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.514
ACN16399.1
Putative amino-acid acetyltransferase.
  
 0.509
acsM4
AcsM4; middle-chain-fatty-acid-acyl-CoA synthetase AcsM4 (AMP-binding protein).
 
 
0.501
acsM2
AcsM2; middle-chain-fatty-acid-acyl-CoA synthetase AcsM2 (AMP-binding protein).
 
 
0.490
hemL
HemL; Glutamate-1-semialdehyde 2,1-aminomutase HemL.
 
  
 0.487
acsM1
AcsM1; middle-chain-fatty-acid-acyl-CoA synthetase AcsM1 (AMP-binding protein).
 
 
0.483
rplB
RplB; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.471
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.