STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpXGlpX; Fructose-1,6-bisphosphatase GlpX (D-fructose-1,6-bisphosphate 1-phosphohydrolase class II) (FBPase II). (328 aa)    
Predicted Functional Partners:
tkt1
Tkt1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.979
ACN16634.1
Putative ketose-bisphosphate aldolase family protein.
  
 
 0.947
talC
TalC; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.943
pgi
Pgi; Glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); Belongs to the GPI family.
    
 0.943
pfkA2
PfkA2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 
 0.926
fba2
Fba2; Fructose-bisphosphate aldolase Fba.
  
 
 0.923
fba1
Fba1; Fructose-bisphosphate aldolase Fba.
    
 0.919
fbp1
Fbp1; Fructose-1,6-bisphosphatase Fbp.
    
 0.916
pfkA
ABC-type branched-chain amino acid transporter, periplasmic substrate-binding protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
   
 
 0.915
pfp
Pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfb.
   
 
 0.915
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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