Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACN15360.1Putative esterase of the alpha-beta hydrolase superfamily. (657 aa)    
Predicted Functional Partners:
ACN15361.1
Sensory box histidine kinase/response regulator.
   
   0.783
ACN16274.1
Predicted polyketide synthase.
  
 0.668
comE
ComE; DNA internalization-related competence protein ComE.
     
 0.559
rpoB
RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.542
ACN14022.1
Putative two domain sensory box histidine kinase (PAS/PAC domain/GGDEF domain protein).
 
   
 0.538
ACN15200.1
Conserved hypothetical protein.
 
 
 0.537
ACN17411.1
Putative two-component system sensor protein.
  
 
 0.535
cyaA2
CyaA2; Adenylate cyclase CyaA (ATP pyrophosphate-lyase) (Adenylyl cyclase).
     
 0.502
ACN15540.1
Two-component hybrid protein, sensory box hisitidine kinase/adenylate cyclase.
  
 
 0.500
rpoZ
RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.500
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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