close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acoAAcoA; Acetoin dehydrogenase E1, alpha subunit AcoA. (328 aa)    
Predicted Functional Partners:
acoB
AcoB; Acetoin dehydrogenase E1, beta subunit AcoB.
 0.999
pdhB
PdhB; Pyruvate dehydrogenase complex, beta subunit PdhB (E1 component).
 0.999
pdhC
PdhC; Dihydrolipoamide acetyltransferase PdhC (pyruvate dehydrogenase complex, E2 component).
 0.997
lplA
LplA; Lipoate-protein ligase A LplA.
 
 
 0.860
lpdA
LpdA; Lipoamide dehydrogenase LpdA (pyruvate dehydrogenase complex, E3 component).
 
 0.802
ACN13842.1
Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes).
 
 0.741
ACN17394.1
Dehydrogenase.
 
 0.739
ACN13735.1
Mercuric reductase (Hg(II) reductase); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.703
ACN14101.1
Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.698
gcvH
GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.682
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.