| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACN15429.1 | uvrB1 | HRM2_23340 | HRM2_23320 | Periplasmic soluble lytic transglycosylase fused to ABC-type amino acid-binding protein (SLT domain fusion protein). | UvrB1; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA prei [...] | 0.779 |
| ACN15429.1 | uvrC | HRM2_23340 | HRM2_23330 | Periplasmic soluble lytic transglycosylase fused to ABC-type amino acid-binding protein (SLT domain fusion protein). | UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.786 |
| ACN17767.1 | mutL | HRM2_47180 | HRM2_31500 | Putative ATP-dependent DNA helicase. | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.928 |
| ACN17767.1 | pcrA1 | HRM2_47180 | HRM2_40570 | Putative ATP-dependent DNA helicase. | PcrA1; ATP-dependent DNA helicase PcrA. | 0.781 |
| ACN17767.1 | uvrA1 | HRM2_47180 | HRM2_08970 | Putative ATP-dependent DNA helicase. | UvrA1; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.603 |
| ACN17767.1 | uvrA2 | HRM2_47180 | HRM2_18540 | Putative ATP-dependent DNA helicase. | UvrA2; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.603 |
| ACN17767.1 | uvrB1 | HRM2_47180 | HRM2_23320 | Putative ATP-dependent DNA helicase. | UvrB1; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA prei [...] | 0.667 |
| ACN17767.1 | uvrB2 | HRM2_47180 | HRM2_26240 | Putative ATP-dependent DNA helicase. | UvrB2; DNA excision repair system, helicase subunit UvrB1. | 0.667 |
| ACN17767.1 | uvrB3 | HRM2_47180 | HRM2_26250 | Putative ATP-dependent DNA helicase. | UvrB3; DNA excision repair system, UvrB2 protein (Excinuclease ABC, subunit B2). | 0.667 |
| ACN17767.1 | uvrB4 | HRM2_47180 | HRM2_26260 | Putative ATP-dependent DNA helicase. | UvrB4; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA prei [...] | 0.667 |
| ACN17767.1 | uvrC | HRM2_47180 | HRM2_23330 | Putative ATP-dependent DNA helicase. | UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.742 |
| mutL | ACN17767.1 | HRM2_31500 | HRM2_47180 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Putative ATP-dependent DNA helicase. | 0.928 |
| mutL | pcrA1 | HRM2_31500 | HRM2_40570 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | PcrA1; ATP-dependent DNA helicase PcrA. | 0.881 |
| mutL | uvrA1 | HRM2_31500 | HRM2_08970 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrA1; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.474 |
| mutL | uvrA2 | HRM2_31500 | HRM2_18540 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrA2; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.474 |
| mutL | uvrB1 | HRM2_31500 | HRM2_23320 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrB1; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA prei [...] | 0.449 |
| mutL | uvrB3 | HRM2_31500 | HRM2_26250 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrB3; DNA excision repair system, UvrB2 protein (Excinuclease ABC, subunit B2). | 0.449 |
| mutL | uvrB4 | HRM2_31500 | HRM2_26260 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrB4; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA prei [...] | 0.449 |
| mutL | uvrC | HRM2_31500 | HRM2_23330 | MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.722 |
| pcrA1 | ACN17767.1 | HRM2_40570 | HRM2_47180 | PcrA1; ATP-dependent DNA helicase PcrA. | Putative ATP-dependent DNA helicase. | 0.781 |
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