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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkB2PfkB2; Carbohydrate kinase family protein PfkB2. (293 aa)    
Predicted Functional Partners:
spsA
SpsA; Sucrose phosphate synthase (HAD-superfamily).
  
 0.985
ACN15522.1
Hydrolase of HAD-superfamily.
 
  
 0.958
ACN15520.1
Alpha amylase family protein.
 
 
 
 0.937
pgi
Pgi; Glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); Belongs to the GPI family.
  
 
 0.933
pfkB1
PfkB1; Carbohydrate kinase family protein PfkB1; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.926
glmS
GlmS; Glucosamine--fructose-6-phosphate aminotransferase (D-fructose-6- phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase).
  
 0.920
pfkA
ABC-type branched-chain amino acid transporter, periplasmic substrate-binding protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
  
 
 0.915
pfp
Pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfb.
  
 
 0.915
pfkA2
PfkA2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 
 0.915
glpX
GlpX; Fructose-1,6-bisphosphatase GlpX (D-fructose-1,6-bisphosphate 1-phosphohydrolase class II) (FBPase II).
    
 0.913
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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