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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adeCAdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (621 aa)    
Predicted Functional Partners:
apt1
Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.944
ACN16857.1
Two-component fusion protein (N:Molybdopterin dehydrogenase, FAD-binding domain-C:Carbon monoxide dehydrogenase medium chain).
 
  
 0.937
apt2
Apt2; Adenine phosphoribosyltransferase Apt.
 
  
 0.934
hpt
Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.932
manC
ManC; Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase ManC; Belongs to the mannose-6-phosphate isomerase type 2 family.
       0.643
xpt
Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
    
 0.591
guaA1
GuaA1; Catalyzes the synthesis of GMP from XMP.
     
 0.535
ACN15555.1
Conserved hypothetical protein.
       0.515
guaD
GuaD; Guanine/cytosine deaminase related protein GuaD.
 
   
 0.484
zupT
ZupT; Heavy-metal cation transporter ZupT.
       0.473
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.