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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topBTopB; DNA topoisomerase III. (855 aa)    
Predicted Functional Partners:
ACN17767.1
Putative ATP-dependent DNA helicase.
 0.972
ACN13337.1
Helicase-family protein; Related to 5' to 3' DNA helicase.
  
 0.968
polA
PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.798
recA
RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.784
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
  
   0.752
ACN17391.1
DNA repair exonuclease family protein.
  
 0.744
rapA
RapA; RNA polymerase associated protein RapA (ATP-dependent helicase HepA).
 
 
 0.679
ACN17965.1
Single-strand binding protein (Helix-destabilizing protein).
  
 
 0.677
gltB2
GltB2; Glutamate synthase [NADPH], large chain (NADPH-GOGAT).
  
  
 0.636
recJ
RecJ; single-stranded-DNA-specific exonuclease RecJ.
  
 
 
 0.591
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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