| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACN16389.1 | fbiC1 | HRM2_33140 | HRM2_33150 | Putative metallo-dependent hydrolase. | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.931 |
| ACN16389.1 | mqnA | HRM2_33140 | HRM2_33130 | Putative metallo-dependent hydrolase. | Putative periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.931 |
| ACN16389.1 | mqnB | HRM2_33140 | HRM2_27040 | Putative metallo-dependent hydrolase. | 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.967 |
| ACN16389.1 | mqnD | HRM2_33140 | HRM2_33090 | Putative metallo-dependent hydrolase. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.675 |
| ACN16389.1 | ubiA | HRM2_33140 | HRM2_45950 | Putative metallo-dependent hydrolase. | UbiA; Predicted 4-hydroxybenzoate polyprenyltransferase UbiA; Belongs to the UbiA prenyltransferase family. | 0.664 |
| ACN16389.1 | vdcC | HRM2_33140 | HRM2_28770 | Putative metallo-dependent hydrolase. | VdcC; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein VdcC; Belongs to the UbiD family. | 0.501 |
| aroQ | fmt | HRM2_27030 | HRM2_27000 | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.741 |
| aroQ | mqnB | HRM2_27030 | HRM2_27040 | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.818 |
| aroQ | rpe | HRM2_27030 | HRM2_27020 | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Rpe; Ribulose-phosphate 3-epimerase Rpe (pentose-5-phosphate 3-epimerase). | 0.819 |
| aroQ | rsmB | HRM2_27030 | HRM2_27010 | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.776 |
| fbiC1 | ACN16389.1 | HRM2_33150 | HRM2_33140 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Putative metallo-dependent hydrolase. | 0.931 |
| fbiC1 | mqnA | HRM2_33150 | HRM2_33130 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Putative periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.964 |
| fbiC1 | mqnB | HRM2_33150 | HRM2_27040 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.966 |
| fbiC1 | mqnD | HRM2_33150 | HRM2_33090 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.982 |
| fbiC1 | ubiA | HRM2_33150 | HRM2_45950 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | UbiA; Predicted 4-hydroxybenzoate polyprenyltransferase UbiA; Belongs to the UbiA prenyltransferase family. | 0.826 |
| fbiC1 | vdcC | HRM2_33150 | HRM2_28770 | FbiC1; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | VdcC; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein VdcC; Belongs to the UbiD family. | 0.814 |
| fmt | aroQ | HRM2_27000 | HRM2_27030 | Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.741 |
| fmt | mqnB | HRM2_27000 | HRM2_27040 | Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.812 |
| fmt | rpe | HRM2_27000 | HRM2_27020 | Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Rpe; Ribulose-phosphate 3-epimerase Rpe (pentose-5-phosphate 3-epimerase). | 0.814 |
| fmt | rsmB | HRM2_27000 | HRM2_27010 | Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.999 |