| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adk | apt1 | HRM2_17050 | HRM2_05200 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.932 |
| adk | apt2 | HRM2_17050 | HRM2_38820 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Apt2; Adenine phosphoribosyltransferase Apt. | 0.932 |
| adk | purA | HRM2_17050 | HRM2_17430 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.508 |
| adk | purB | HRM2_17050 | HRM2_27090 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.956 |
| adk | purD | HRM2_17050 | HRM2_09300 | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | PurD; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. | 0.568 |
| apt1 | adk | HRM2_05200 | HRM2_17050 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.932 |
| apt1 | apt2 | HRM2_05200 | HRM2_38820 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Apt2; Adenine phosphoribosyltransferase Apt. | 0.900 |
| apt1 | purA | HRM2_05200 | HRM2_17430 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.450 |
| apt1 | purB | HRM2_05200 | HRM2_27090 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.949 |
| apt1 | purD | HRM2_05200 | HRM2_09300 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurD; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. | 0.770 |
| apt1 | purH1 | HRM2_05200 | HRM2_33050 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ]. | 0.944 |
| apt1 | purH2 | HRM2_05200 | HRM2_33060 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurH2; Bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase]. | 0.944 |
| apt1 | purL | HRM2_05200 | HRM2_17180 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule f [...] | 0.766 |
| apt2 | adk | HRM2_38820 | HRM2_17050 | Apt2; Adenine phosphoribosyltransferase Apt. | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.932 |
| apt2 | apt1 | HRM2_38820 | HRM2_05200 | Apt2; Adenine phosphoribosyltransferase Apt. | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
| apt2 | purA | HRM2_38820 | HRM2_17430 | Apt2; Adenine phosphoribosyltransferase Apt. | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.435 |
| apt2 | purB | HRM2_38820 | HRM2_27090 | Apt2; Adenine phosphoribosyltransferase Apt. | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.948 |
| apt2 | purD | HRM2_38820 | HRM2_09300 | Apt2; Adenine phosphoribosyltransferase Apt. | PurD; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. | 0.770 |
| apt2 | purH1 | HRM2_38820 | HRM2_33050 | Apt2; Adenine phosphoribosyltransferase Apt. | PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ]. | 0.943 |
| apt2 | purH2 | HRM2_38820 | HRM2_33060 | Apt2; Adenine phosphoribosyltransferase Apt. | PurH2; Bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase]. | 0.943 |