STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACN15866.1Sigma-54 dependent two component DNA-binding response regulator (Fis family protein). (467 aa)    
Predicted Functional Partners:
rpoN
RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.953
pyrC
PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.820
pyrB
PyrB; Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.814
lepB
LepB; Signal peptidase I (SPase I); Belongs to the peptidase S26 family.
       0.692
ACN15332.1
Putative pilS, sensory histidne kinase.
 
 
 0.604
ACN15865.1
Hypothetical protein.
       0.531
cheA2
CheA2; Chemotaxis protein CheA.
  
 
 0.501
ACN17240.1
Sensory box hisitidine kinase.
 
 
 0.460
ACN15870.1
Conserved hypothetical protein.
       0.453
flhA
FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.426
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.