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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaDGuaD; Guanine/cytosine deaminase related protein GuaD. (419 aa)    
Predicted Functional Partners:
ACN16857.1
Two-component fusion protein (N:Molybdopterin dehydrogenase, FAD-binding domain-C:Carbon monoxide dehydrogenase medium chain).
 
 
 0.964
hpt
Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.929
xpt
Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
 
 0.908
apt1
Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.908
apt2
Apt2; Adenine phosphoribosyltransferase Apt.
     
 0.908
ACN15935.1
Conserved hypothetical protein.
       0.773
gcvP2
GcvP2; Glycine cleavage system, dehydrogenase subunit GcvP2.
 
 
  
 0.643
coxL
CoxL; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL.
 
  
 0.565
coxS
CoxS; Aerobic-type carbon monoxide dehydrogenase, small chain CoxS.
 
  
 0.496
adeC
AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
 
   
 0.484
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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