STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACN16327.1Glyoxalase/dioxygenase/bleomycin resistance family protein. (134 aa)    
Predicted Functional Partners:
sbm
Sbm; Homodimeric methylmalonyl-CoA mutase Sbm (MCM-alpha).
  
 0.994
argK
ArgK; LAO/AO transport system kinase.
  
 0.982
pccB
PccB; propionyl-CoA carboxylase PccB (carboxyltransferase).
 
 
 0.878
sdhC
SdhC; Succinate dehydrogenase/fumarate reductase, cytochrome b containing subunit SdhC.
  
  
 0.689
mcmL
McmL; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
  
 0.669
ACN16274.1
Predicted polyketide synthase.
  
 
 0.650
sucC1
SucC1; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.624
mmc
Mmc; Methylmalonyl-CoA carboxylase (12S subunit).
  
 
 0.608
gcdA1
GcdA1; glutaconyl-CoA decarboxylase GcdA.
  
 
 0.608
sdhB
SdhB; Succinate dehydrogenase/fumarate reductase, iron-sulfur containing subunit SdhB.
  
  
 0.568
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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