STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pksPks; Polyketide synthase Pks; Belongs to the acetyltransferase family. (139 aa)    
Predicted Functional Partners:
argJ
ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
 
 0.991
argB
ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.988
argG
ArgG; Argininosuccinate synthase ArgG (Citrulline--aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.967
argA2
ArgA2; Amino-acid acetyltransferase ArgA (N-acetylglutamate synthase) (AGS) (NAGS); Belongs to the acetyltransferase family. ArgA subfamily.
 
 
0.959
argC
ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 
 0.944
argF
ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
  
 0.933
gdhA1
GdhA1; NADP-specific glutamate dehydrogenase GdhA (NADP-GDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.928
argH2
ArgH2; Argininosuccinate lyase ArgH (Arginosuccinase) (ASAL).
  
  
 0.922
ACN16221.1
Putative aspartate/tyrosine/aromatic acid aminotransferase.
  
 
 0.910
gdhA2
GdhA2; NAD-specific glutamate dehydrogenase GdhA (NAD-GDH).
     
  0.900
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.