Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mreBMreB; Rod shape-determining protein MreB. (348 aa)    
Predicted Functional Partners:
mreC
MreC; Involved in formation and maintenance of cell shape.
 
 
 0.998
mrdA
MrdA; Penicillin-binding protein MrdA (PBP) (transpeptidase).
 
 
 0.968
rodA
RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.963
ACN16591.1
Putative rod shape-determining protein MreD.
       0.817
ACN15225.1
Hypothetical protein.
  
 
 0.803
ACN16364.1
Hypothetical protein.
  
 
 0.803
ACN17060.1
Lambda repressor-like DNA-binding family protein.
  
 
 0.799
ftsZ
FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.784
hdrD3
HdrD3; Heterodisulfide reductase, subunit HdrD3 (HdrCB homologue protein).
   
   0.771
ftsW
FtsW; Cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.761
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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