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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apt2Apt2; Adenine phosphoribosyltransferase Apt. (186 aa)    
Predicted Functional Partners:
guaA1
GuaA1; Catalyzes the synthesis of GMP from XMP.
  
 0.990
gmk
Gmk; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.955
purB
PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.948
purH1
PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ].
  
 0.943
purH2
PurH2; Bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase].
  
 0.943
adeC
AdeC; Adenine deaminase AdeC; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
 
  
 0.934
adk
Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.932
hpt
Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.923
ushA
UshA; UDP-sugar hydrolase / 5'-nucleotidase UshA [precursor]; Belongs to the 5'-nucleotidase family.
    
 0.912
guaD
GuaD; Guanine/cytosine deaminase related protein GuaD.
     
 0.908
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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