STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
caiC3CaiC3; acyl-CoA synthetase (AMP-forming)/AMP-acid ligase CaiC. (574 aa)    
Predicted Functional Partners:
acsM2
AcsM2; middle-chain-fatty-acid-acyl-CoA synthetase AcsM2 (AMP-binding protein).
 
 
 0.907
bioF
BioF; 7-keto-8-aminopelargonate synthetase BioF.
 
 
 0.898
acsL3
AcsL3; long-chain-fatty-acid-CoA ligase AcsL3 (AMP-binding protein).
 
     0.891
ACN16274.1
Predicted polyketide synthase.
  
 0.887
dnaN
DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for [...]
     0.861
acd16
Acd16; Short-chain specific acyl-CoA dehydrogenase/oxidase Acd16 (butyryl-CoA dehydrogenase).
 
  
 0.859
fadD3
FadD3; long-chain-fatty-acid--CoA ligase FadD3 (Acetyl-CoA-synthetase) (Acyl-activating enzyme).
 
    
0.778
acd4
Acd4; Short-chain specific acyl-CoA dehydrogenase/oxidase Acd4 (butyryl-CoA dehydrogenase).
 
  
 0.776
acd14
Acd14; Short-chain specific acyl-CoA dehydrogenase/oxidase Acd14 (butyryl-CoA dehydrogenase).
 
  
 0.714
hemL
HemL; Glutamate-1-semialdehyde 2,1-aminomutase HemL.
 
  
 0.703
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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