Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ACN17112.1HD-GYP domain family protein. (470 aa)    
Predicted Functional Partners:
ACN17113.1
Sensory box histidine kinase (GGDEF domain protein).
 
 
 0.852
ACN17548.1
Response regulator.
 
  
 0.774
ACN14745.1
Metal dependent response regulator.
 
  
 0.760
ACN13389.1
Conserved hypothetical protein.
  
     0.759
ACN16970.1
HD-GYP hydrolase domain family protein.
  
     0.664
ACN16797.1
Predicted two-component system transcriptional regulator.
 
   
 0.624
pcrA1
PcrA1; ATP-dependent DNA helicase PcrA.
       0.544
ACN17172.1
Putative 3',5'-cyclic-nucleotide phosphodiesterase.
 
   
 0.517
ACN13201.1
Signal transduction family protein (GGDEF domain protein).
 
  
 0.509
algC
AlgC; Phosphomannomutase/phosphoglucomutase AlgC.
       0.503
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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