STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (284 aa)    
Predicted Functional Partners:
putA1
PutA1; Bifunctional protein PutA [Includes: Proline dehydrogenase; P5C dehydrogenase].
   
 0.947
putA2
PutA2; NAD-dependent aldehyde dehydrogenase PutA; Belongs to the aldehyde dehydrogenase family.
 
 
 0.944
proB
ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.942
prdF1
PrdF1; Proline racemase PrdF; Belongs to the proline racemase family.
    
 0.916
prdF2
PrdF2; Proline racemase PrdF; Belongs to the proline racemase family.
    
 0.916
pflD1
PflD1; Formate C-acetyltransferase PflD1 (Pyruvate formate-lyase 1).
    
 0.911
pflD2
PflD2; Formate C-acetyltransferase PflD2 (Pyruvate formate-lyase 2) PflD2.
    
 0.911
proA
ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.849
ACN15408.1
Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.754
guaA1
GuaA1; Catalyzes the synthesis of GMP from XMP.
     
 0.561
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.