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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
umuD2UmuD2; DNA polymerase V/DNA repair protein UmuD; Belongs to the peptidase S24 family. (139 aa)    
Predicted Functional Partners:
umuC1
UmuC1; DNA repair protein UmuC.
 
 
 0.975
recA
RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.966
umuC2
UmuC2; DNA-repair protein UmuC1 (Nucleotidyltransferase protein).
 
 
 0.897
ACN13509.1
DNA-directed DNA polymerase.
 
 
 0.896
ACN17148.1
Hypothetical protein.
       0.773
ACN17149.1
Fe-S oxidoreductase family protein.
       0.693
ACN15893.1
Conserved hypothetical protein.
   
  
 0.670
dinP
DinP; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.663
recN
RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.648
trpC
TrpC; Tryptophan biosynthesis protein TrpC (anthranilate synthase complex).
     
 0.522
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.