STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabH3FabH3; 3-oxoacyl-acyl carrier synthase III FabH3. (336 aa)    
Predicted Functional Partners:
ACN16274.1
Predicted polyketide synthase.
  
  
 0.989
fabG4
FabG4; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.975
ACN16399.1
Putative amino-acid acetyltransferase.
  
  
 0.933
fabH2
FabH2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 
0.929
fabG5
FabG5; 3-oxoacyl (acyl-carrier protein) reductase FabG5.
 
 
 0.925
ACN15446.1
Putative multi-domain beta-ketoacyl polyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.909
pdhC
PdhC; Dihydrolipoamide acetyltransferase PdhC (pyruvate dehydrogenase complex, E2 component).
  
 
 0.834
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
  
 
 0.822
gltA1
GltA1; Citrate (si)-synthase GltA1; Belongs to the citrate synthase family.
    
 0.808
gltA3
GltA3; Citrate (si)-synthase GltA2; Belongs to the citrate synthase family.
    
 0.808
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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