STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACN17659.1Cobalamin-dependent methionine synthase, B12-binding:Coenzyme B12-binding. (210 aa)    
Predicted Functional Partners:
metH4
MetH4; vitamin-B12 dependent methionine synthase MetH (5-methyltetrahydrofolate--homocysteine methyltransferase).
  
 0.987
ACN17453.1
Methionine synthase I, cobalamin-binding domain protein.
  
 0.982
metH1
MetH1; vitamin-B12 dependent methionine synthase MetH (5-methyltetrahydrofolate--homocysteine methyltransferase).
  
 0.978
metH2
MetH2; vitamin-B12 dependent methionine synthase MetH (5-methyltetrahydrofolate--homocysteine methyltransferase).
  
 0.978
metH3
MetH3; vitamin-B12 dependent methionine synthase MetH (5-methyltetrahydrofolate--homocysteine methyltransferase).
  
 0.938
ACN16953.1
Ferredoxin (4Fe-4S iron-sulfur cluster binding protein).
 
    0.633
ACN17658.1
Putative glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
       0.529
fdx7
Fdx7; 4Fe-4S ferredoxin, iron-sulfur binding family protein Fdx7.
 
    0.498
hemE
HemE; Uroporphyrinogen decarboxylase HemE (URO-D); Belongs to the uroporphyrinogen decarboxylase family.
  
 0.482
mttB6
MttB6; Trimethylamine methyltransferase MttB (TMA methyltransferase).
   
 0.443
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.