close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXMetX; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (403 aa)    
Predicted Functional Partners:
ACN17707.1
S-adenosylmethionine-dependent (SAM) methyltransferase.
  
 0.998
hom
Homoserine dehydrogenase Hom.
 
 0.976
ACN17636.1
Probable aspartokinase (Aspartate kinase); Belongs to the aspartokinase family.
   
 0.971
glyA
GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.838
ACN14464.1
Phosphoserine phosphatase.
   
 
 0.819
serB
SerB; Phosphoserine phosphatase SerB (PSP).
   
 
 0.817
trpB
TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.811
ACN13932.1
Aminotransferase, class V (putative purine catabolism protein PucG).
     
  0.800
trpA
TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
ACN17597.1
Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.800
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.