STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACN17822.1Conserved hypothetical protein. (173 aa)    
Predicted Functional Partners:
serA2
SerA2; D-3-phosphoglycerate dehydrogenase (PGDH) SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.773
ACN17823.1
Putative heme biosynthesis protein.
       0.773
purF
PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.773
carB2
CarB2; Carbamoyl-phosphate synthase, large subunit CarB2; Belongs to the CarB family.
       0.773
carA
CarA; Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family.
       0.773
ACN17827.1
Putative pyridine nucleotide-disulfide oxidoreductase.
       0.671
nudC
NudC; NADH pyrophosphatase NudC; Belongs to the Nudix hydrolase family. NudC subfamily.
       0.661
ACN17828.1
Glutamate synthase; Belongs to the glutamate synthase family.
       0.653
ACN17829.1
Conserved hypothetical protein.
       0.653
glnE
GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicate [...]
       0.427
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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